Showing posts with label gotham. Show all posts
Showing posts with label gotham. Show all posts

Monday, December 29, 2014

Manhattan's OTHER Project : Gotham's penicillin un-superheroes (and why they are ignored by academics)

If another secretive, undemocratic, big science Manhattan Project is more likely to cause a global environmental disaster (think nuclear winter or geo-engineering) than prevent it - then does the experiences of wartime Gotham have anything at all to still teach us, as we face global climate meltdown ?

Well, unbeknownst to virtually all, Manhattan actually had another ( far different) wartime project that still has lessons for today.

Its global effect were almost as big as that of the much better known atomic Manhattan Project, but by pointed contrast to it, it was near universally always warmly received worldwide.

Because Manhattan's real enduring gift to humanity during and after the war years was not The Bomb (or the infamous Norden Bombsight) but rather bog-ordinary cheap available-to-all public domain natural penicillin. You know - the stuff the academics are always telling us that the British gave us.

Now I sometimes joke that the only reasons the Scandinavians didn't give a joint Nobel Peace Prize to Stalin and Hitler was because the Nordics ran out of time - the guys died first.

But joking aside, the Nobel prize choices have rarely stood up well to the test of time.

Admittedly, Mr Nobel's naive requirements that everything significant that is discovered or invented was brought to mass use or mass knowledge by no more than three (still living) individuals does force the Nobel prize selection committees into mindless contortions.

Still - what of earth were the Nordics thinking - or not thinking - when the medicine committee gave the 1945 Nobel prize for penicillin to Fleming and Florey ?

After his 1928 discovery, Alec Fleming's main contribution was to tell everybody within earshot (for 15 wasted years) that penicillin would only work if used as a topical antiseptic (it doesn't work well there) and would NEVER work if taken internally (when in fact it works miraculously well there.)

Moreover he said it would never be useful for patients until artificially synthesized when in fact it never has : all clinical penicillin and the bulk of all of today's antibiotics (yes even today !) are still derived from natural penicillin made by fungus.

In this particularly obtuse claim, he was more than fully supported by chemist manque Howard Florey.

In fact Florey led the Allies' wartime charge to repeatedly try and to repeatedly fail to make penicillin by artificial (patentable) methods, rather than to simply produce enough natural (public domain) penicillin to meet current desperate wartime needs.

And Florey and Fleming, both strong supporters of the Conservative Party, fully backed the Conservative politicians in Britain's wartime coalition government who wanted to limit wartime penicillin production to only lightly wounded front line troops.

None for severely wounded troops or any home front civilians in Allied nations and colonies; none for civilians in Neutral, Occupied or Enemy countries - none for Allied POWs, let alone for enemy POWs !

All this because it had been determined that diverting British resources to set up enough British natural penicillin bottle plants in unused buildings to supply all military and civilian needs for the world (and thus to secure a postwar Pax Britannica based on this wartime humanitarian effort) would cost about ten million pounds.

And that was also enough for at least one or two more additions to Bomber Command's already many heavy bomber squadrons.

Since 1932 and Prime Minister Baldwin's famous speech, it had been become the 40th Article of the Conservative Party faith that 'the bomber always gets through' and that destroying people and not saving them was the Conservative way to the moral high ground and winning any war.

But what really made wartime penicillin the world's best known/best loved medicine is that as the last dying act of the New Deal, a new Pax Americana had suddenly made cheap non-patented (natural) penicillin abundantly available to all - wartime friend and foe alike.

But none of these good guys , none of the Americans (and a Canadian) centred in NYC who were mostly responsible for this boon to humanity, ever received a Nobel Prize or public acclaim for the miracle of cheap-penicillin-for-all : only the bad guys.

Because the good guys' approach couldn't have been more different than the atomic Manhattan project.

They were open about their intentions and pragmatically and morally committed to saving the little guy. They wasted little taxpayer money and resources and instead combined a 'little science' approach with a ruggedly low tech engineering style.

All of this was anathema to academics (including non scientists like historians) who wanted to ballyhoo the supposed wartime triumphs of heavily taxpayer funded basic science-big science as a way to getting the taxpayer to permanently fund their postwar hobbyhorses.

So - in a brazen conflict of interest and in violence to the known facts - academics have tended to give all the penicillin acclaim to the big science advocates (cum penicillin bad guys).

To those who were actually most dedicated to keeping wartime penicillin a much delayed, scarce and patented exclusive drug.

So Drs Florey and Fleming in Britain , along with Drs A N Richards and Chester Keefer in the States , got all the acclaim.

Logrolling is what they call this sort of stuff it in politics - I don't know what they call it inside the ivory tower bunker : false weighting of the scales of evidence maybe ?

Wednesday, December 17, 2014

Noir's Children : the teenagers who MADE Mo go Po

Noir's Children (my particular birth cohort of 1940-1956) those of us born 'after the Fall of France but before the Rise of Elvis' - were virtually unique in being perfectly comfortable living inside TWO whales .

Those two whales being the Modernity (Mo) of our childhood and early teen years and the emerging Post Modernity (Po) of our late teen years and early adult years.

We still remain unique in this regard - we are old enough to remember believing in our elders' tattered Modernity but with minds not so rigidly formed we couldn't also take on the attributes of an emerging Post-Modernity - which was the only reality our younger siblings ever knew first hand.

My cohort did not just feel the transition from one era to another : we were that transition.

Modernity only died when it failed to reproduce itself in its young


For it was our failure to carry on the ideas of Modernity as we matured that condemned Modernity to a slow sad certain death as our  still-faithful elders died off, one by one.

Why our post WWII birth cohort - and not any earlier birth cohorts - came to reject the centuries-old Enlightenment Project is the subject of this blog and of my book projects .

And like many exciting things, it all begins in wartime Gotham  - where the reigning American Super Hero was not the comic books' Superman, Batman or Captain America but rather a squat balding middle aged Dutch-Swiss-American called Carl Norden.

His invention , a bombsight that was claimed to unerringly drop a bomb into a pickle barrel from three miles up - was going to end the war ( even end all wars) quickly, cheaply and with minimum loss of civilian lives.

As a result, the British and American governments of the day in 1940 saw no need for spending serious amounts of taxpayers' monies on either atomic bomb or penicillin development.

In their experts' eyes, the atomic bomb was serious overkill (literally) and life-saving penicillin, rather like old fashioned infantry riflemen, wasn't really going to be needed in a short modern war of minimum casualties.

The best laid plans .....

Monday, December 8, 2014

Martin Henry Dawson : against a city - and an age - of Super Heroes, the story of an un-superhero

1875 -1965 was an age of Scientism and of Super (hyper) Modernity --- an era of unlimited faith in the abilities of technocratic elites (a view at least held by other technocratic elites).

An epoch hearing many (un-democratic) proposals for elite corps of skygod-like air police to short sharply govern the real world of unruly adults down below.

Fiction writers matched the non-fiction intellectuals by creating imaginary super-heroes doing basically the same job as the proposed  Air Police , to populate the fantasy world of male teens and boys.

It has been largely and deliberately forgotten today* that these schemes for an elite air police force to govern all the world were openly proposed and critiqued by many seriously respected intellectuals such as HG Wells.

It was as if the Greek and Roman skygods of ancient thought were to be adapted to modern times.

Little wonder then that the same young men who read everything vaguely Sci-Fi that HG Wells ever wrote , eagerly took up this idea for their various (Gotham based) comic book super heroes.

It pleasures me muchly then to be able to push hard against this grain and focus in on a story , set in that same Gotham as in the heyday of the Golden Age Super Heroes, that features a crusading scientist who positively oozed un-charisma.

Someone as un-superheroic and as un-skygod like as can possibly be.

Who yet did great things ....

__________

* PD Smith's The Doomsday Men is one sturdy exception .

There have been actually a fair number of other books and authors that have been successful in developing this theme : H Bruce Franklin's War Stars springs to mind.

Successful in the academic world that is , but not yet in the popular consciousness.

Thursday, October 23, 2014

What superheroes are not : not inventors, discoverers, doctors,firemen , teachers , thinkers

Mother Teresa --- with an assault rifle


It is well known that all the superpower violence of the superheroes is designed only to save us from bad guys -- what could possibly be wrong with that moral stance ?

Saving an "us" who is not totally good but not really very bad either, from bad guys who are totally bad .

Well for starters, one might reply  that in the real world the good and bad guys rarely morally divide up as neatly as all that , under all circumstances.

Again, we might ask how do the superheroes marvellously manage save us with all that superpower violence without that same violence being lethal to human lives ?

They do seem rather like a fairy tale version of the real world US Air Force.

They superheroes are like super-efficient military pilots who somehow always destroy German - Japanese - North Korean - North Vietnamese - Iraq et al war factories ... without ever killing any nearby civilians or factory employees.

And even as fairy tale heroes, the superheroes are also heroes of the narrowest sort.

These superheroes are never heroic firemen or doctors, never inventing or discovering something that helps make human life better.

Nor heroes who inspire us by word and thought - never a public teacher (in the formal sense) or a public intellectual.

Never a saint - never selfless love for humanity even at the cost of their own deaths (no agape love).

Because the superhero is always very moral without ever being very mortal - which rather takes the sting out of their acts of bravery on our behalf.

Moral Flaws in the Superhero Model


The superheroes' original creators keenly wanted to do the right thing - fight all the bad people of the 1930s - but they failed morally.

They were physically and culturally small people in a world that exalted the big.

Big physically fit people, big battleships, big tanks, big bombers, big nations, big corporations , big hydro dams and on and on.

Tragically the superhero creators accepted their era's mantra that 'bigger was better' ---  even if in a a highly selective way.

To these comic book creators, 'bigger was better' was reduced or restricted to 'bigger is potentially morally better in practise' .

Because they felt that big goodness is the only practical way to defeat big badness.

And their super bigness was a solo super powerful America defeating the Axis all on its own.

But imagine a 2014 NATO response to a 1939 German threat to invade Poland.

Now we'd see two dozen nations, virtually all much smaller than Germany (but collectively much bigger) all vowing to go to war together, unless Germany backed off.

This is a viable alternative to the DC universe's solo superpower approach--- and the way that WWII was actually won.

WWII America - even allied to England and Great Russia - could never have defeated the Axis if the rest of the world had remained a hostile Neutral to their cause : from Canada to Liberia to the Free Danes, the small nations all helped.

And remember that the badness the superheroes combat is always highly visible, unsubtle, overt.

Morally easy stuff.

They concentrate on defeating bad guys robbing a poor grandmother with a gun on a public street corner.

Never do they work against the subtle and complex systemic circumstances that made her poor in the first place.

Or that led so many others to consider being a violent robber knocking off harmless old ladies as a better job than years of occasional part time work at minimum wages.

I think there are other ways to be a hero than obtaining the super powers that make inflicting violence risk free.

Dr Dawson's tiny team of misfits and unfits is set in the same 1940 Gotham as the original superheroes but it offers an alternative example of what a non-DC Universe, with un-super heroes - might look like ...

Thursday, September 18, 2014

I'm a thinkin' : maybe its the Gotham EIGHT ?

I've always regarded the number of Gotham's 'unfits' who rescued natural lifesaving penicillin and set it free to do good as being just seven in number but now I am thinking that I was wrong.


First, the two unfit clinicians, Dr Henry Dawson and his assistant Dr Thomas Hunter.

Then three other unfits who greatly assisted them (Dawson's wife Marjorie Granger Dawson, his friend and ex-patient Floyd Odlum , and his ex-patient Dr Dante Colitti).

Finally, the two unfit patients, Charles Aronson and Ms H. H. , whose continued survival under Dawson's pioneering treatment, despite repeated setbacks, allowed the program time to finally succeed in spades.

But I now realize that these seven unfits didn't need to have gotten involved in the first place.

Not if the eighth Gotham 'unfit' , the penicillium notatum. had been accepted on its own considerable merits instead of being dismissed on sight as too small, too simple, too weak and too too disgusting.

But the God of the Modern Era (from the 1870s to the 1960s) was always on the side of the biggest battalions and the Moderns saw most of the world as being on the unworthy-of-life side of the fit/unfit question.

But they were dead wrong.

Because in fact the greatest medical blessing this world has ever seen was brought to us by a handful of unfit doctors serving unfit patients with unfit medicine.

Their unexpected victory in 1945 did not spell the immediate end of the Modern Era and the immediate rise of our present post-Modern Era.

 But it certainly spelt the beginning of that end...

Friday, September 5, 2014

How a handful of Gotham unfits rescued the unbroken bronco of modern medicine (un-patentable natural lifesaving penicillin-for-all) and set it free to do good

When your life hangs in the balance because of bacterial infection and all else has failed, hospitals reach for Plan G - a needleful of Penicillin G - 87 years old and still our most potent , safest and yet by far the cheapest lifesaver.

Big Pharma practically giving away its most potent and yet safest lifesaver - that hardly sounds like the Big Pharma you and I know --- and hate !

Penicillin still remains un-patentable - still remains made naturally by tiny bugs in a bottle , not by human chemists in a factory.

It still finds its main use as an internal lifesaver not as an external antiseptic for cuts and scrapes.

And it still is a widely available lifesaver - regardless of skin color or lack of income .

Partly because it is cheap because it is un-patentable so no one firm or nation can control its production  but mostly because making it available for all is a longstanding tradition since the last year of WWII.

But if Alexander Fleming , that Presbyterian-raised Scot from Old Scotland had had his will, none of this good news would have happened.

Thankfully, another Presbyterian-raised Scot , but this time from New Scotland (Henry Dawson), was there to thwart his will ...



Tuesday, September 2, 2014

The Big Apple's (green) un-super heroes

The biggest horse races offer the biggest prize money so every jockey naturally wants to win big in the biggest of Big Apples - New York City.

Nothing living and green is implied in the term  --- nothing beyond the green colour of cold hard cash.

Its ironic then, isn't , that wartime's penicillium green grew best in The Big Apple's (The Green Apple's ?) concrete jungle.

Not in leafy green Oxford University.

Brewed up in Gotham by Henry Dawson's small group of unfits, misfits and rebels - fermenting up a revolution in how the world of medicine now views the natural world....

Saturday, August 30, 2014

Gotham's wartime unfits rescued natural lifesaving penicillin-for-all


Wartime Gotham's concrete jungle was crawling with comic book Super Heroes and their opponents.

After all ,most of today's best known super heroes were created during the war years.

These Super Heroes did their stuff on some very mean streets that also managed to look a whole lot like the actual streets of Manhattan , circa 1940.

(And more than seventy five years later, they still do !)

I find it hard to feel totally upbeat about Super Heroes - they hold too many overtones of 1940 Hitler's Ubermensch to make me very comfortable.

I can't accept that people who aren't physically extraordinary - or indeed not even ordinarily physical fit - can't make perfectly good heroes.

In fact, I'd argue their task of heroism is much harder to achieve .

because they are not blessed with either Superman's gift of super-special physical powers or Batman's extraordinary-honed human skills (and wealth).

In that same concrete jungle that was 1940 Gotham for example ,Dr Henry Dawson's team of unfits could hardly muster a half dozen ordinarily full functioning limbs between them.

But who can say than anything morally greater ever came out of WWII's bad news war than their unlikely success in rescuing natural lifesaving penicillin-for-all from the meanness of the Allied medical-scientific establishment?

Wednesday, August 27, 2014

Blog's background tiled image is of the oppressive walls of CUMC circa 1928

I am trying to think of visual ways to convey the sheer unexpectedness of the wartime triumph of Manhattan natural penicillin.

What tab-dropping novelist would ever dare suggest that the attempts to create artificial penicillin blossomed in Oxford University's leafy green setting while the successful effort to bring naturally grown penicillin to the world's dying would emerge from Gotham's concrete jungle ?

Even Superman and Spider Man might be taken back to think something as green as natural penicillin would actually bloom among Gotham City's concrete skyscrapers.

When we think of NYC 's biggest private sector employers we probably  think first of finance's Wall Street, advertising's Madison Avenue, fashion's Seventh Avenue, or of broadway theatres, publishing and media headquarters.

But actually NYC's largest private sector employer is a hospital : the world famous CUMC (Columbia University Medical Center) with its thousands of high tech beds and its tens of thousands of daily outpatient visitors.

And so it was that one of 1940 Manhattan's most impressive concrete skylines wasn't set in Midtown at all.

Instead that vista was the sight of CUMC's massed hospital windows set into concrete, endlessly repeating row on row on row.

It certainly helped that Columbia Presbyterian  had an inherently dramatic location (by design) -- boldly sited high on top of a hill of sheer rock in uppermost Manhattan.

In this unlikely setting, this high tech concrete jungle , this modernist temple to reductionist chemistry , Dr Henry Dawson's tiny team tried to set up 700 two litre flasks of natural penicillium spores - all in the face of passive resistance from CUMC's ever-forward-thinking administrators.

About the best way to kill penicillium is to jostle it from room to room to room and that is exactly what the administrators ensured would happen.

Every other professor seemed to have a higher priority than Dawson on the dean's list of potential labs , so that every vacant room he secured as a nursery for his green friends had to be quickly given up.

Finally , he got use of the tiny space beneath each student's seat in the hospital's big two storey teaching amphitheatre.

The warmth from the butt of each slumbering early morning male med student became like a brood hen to the delicate charges below.

(I am not making this stuff up !)

In typical New York City fashion, even the fire escapes were put to good use - used to let the arid pungent smell of penicillium juice waft out onto Broadway crowds rather than to offend the sensitive noses of the hospital's bosses.

A decidedly concrete jungle setting for an early post-modern attempt to return to a new relationship with Mother Nature.

To help convey the overwhelmingly oppressive sight of CUMC's walls , where even a top surgeon - let alone a humble patient or penicillium spore - is but a mere cog , I  made a tile out of a tiny fragment from an old 1928 era photograph of CUMC.

That tile is now the oppressive concrete jungle backdrop to this blog.

I know I can do much better - possibly by smearing a spot of green penicillium in the center of each window ?

We'll see...